El Patroness is the first foal and so far only runner out of Sure You Can (O'Reilly), who won two races in the city.

Second dam Not Sure (Masterclass) won five races. She is the dam of Surely Sacred (Rock 'N' Pop), winner of two Group 2 races including the Gr.2 Avondale Guineas and third in the Gr.1 Australian Derby, and Betwixt (O'Reilly), a full-sister to Sure You Can, who won the Gr.3 Tasmanian Derby and produced Provocative (Zabeel), winner of the Gr.1 Queensland Oaks. Not Sure is a half-sister to Taupo Retreat (Centaine), winner of the Gr.1 November Handicap.

Third dam Icelette (Icelandic) won two Listed races in New Zealand and is the dam of Taupo Retreat, a Group 1 winner in South Africa. She is a half-sister to Stardette, winner of the Gr.3 Eulogy S.

After El Patroness, Sure You Can produced fillies by Shamus Award and Star Witness, followed by a colt by Puissance De Lune foaled in late October. She was covered again by Shamus Award last spring.