Santiago is out of Wadyhatta (Cape Cross).

Second dam Thamarat (Anabaa) was third in the Listed Prix Yacowlef and has produced three black-type horses, among them Motamarris (Le Havre), third in the Gr.1 Prix du Jockey Club, and Riqa (Dubawi), placed in several Listed races. Riqa is the dam of Tantheem (Teofilo), winner of the Gr.3 Prix de Cabourg, the Gr.3 Prix de Meautry and the Gr.3 Prix du Petit Couvert.

The third dam, a winning half-sister to Anabaa Blue (Anabaa), has bred four black-type horses, headed by Thamarat and the sire Tamayuz (Nayef), winner of the Gr.1 Prix Jacques le Marois and the Gr.1 Prix Jean Prat.

Fourth dam Allez Les Trois (Riverman) won the Gr.3 Prix de Flore and produced Anabaa Blue, winner of the Gr.1 Prix du Jockey Club and a sire. She is related to Urban Sea (Miswaki), winner of the Gr.1 Prix de l'Arc de Triomphe and an exceptional broodmare, which connects Santiago with Galileo and Sea The Stars. Through fifth dam Allegretta (Lombard), grandam of Galileo and Sea The Stars, this is also the family of King's Best, winner of the Gr.1 2000 Guineas and a sire.

Wadyhatta has the unraced 2-year-old filly La Joconde (Frankel) and a yearling filly, also by Frankel.